# Universal differential equations in system Biology

**URL:** <https://community.epinowcast.org/t/universal-differential-equations-in-system-biology/362>\
**Category:** Uncategorized\
**Created:** [8 December 2025 17:35 UTC](https://community.epinowcast.org/t/universal-differential-equations-in-system-biology/362 "2025-12-08T17:35:06Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![samabbott](https://dub1.discourse-cdn.com/flex005/user_avatar/community.epinowcast.org/samabbott/32/5_2.png) [@samabbott](https://community.epinowcast.org/u/samabbott)\
**Post date:** [8 December 2025 17:35 UTC](https://community.epinowcast.org/t/universal-differential-equations-in-system-biology/362/1 "2025-12-08T17:35:06Z")

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Really nice paper on universal differential equations in systems biology with some nice looking Julia code.

[https://www.nature.com/articles/s41540-025-00550-w](https://www.nature.com/articles/s41540-025-00550-w)

Code: [GitHub - m-philipps/ude\_pipeline\_systemsbio](https://github.com/m-philipps/ude_pipeline_systemsbio)

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**Author:** ![sambrand](https://avatars.discourse-cdn.com/v4/letter/s/c37758/32.png) [@sambrand](https://community.epinowcast.org/u/sambrand)\
**Post date:** [11 December 2025 15:25 UTC](https://community.epinowcast.org/t/universal-differential-equations-in-system-biology/362/2 "2025-12-11T15:25:26Z")

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Neat stuff!

Its nice to see a paper where someone actually bothers to demo the “common wisdom”, i.e. multi-start optimisation rather than either just doing it because “you know” its better or not doing it at all (or secretly doing it and only showing the inits that work)

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**Author:** ![samabbott](https://dub1.discourse-cdn.com/flex005/user_avatar/community.epinowcast.org/samabbott/32/5_2.png) [@samabbott](https://community.epinowcast.org/u/samabbott)\
**Post date:** [5 January 2026 15:08 UTC](https://community.epinowcast.org/t/universal-differential-equations-in-system-biology/362/3 "2026-01-05T15:08:40Z")

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Yes I agree. Just organising to get these folks to come and give a seminar
